Can You Take Iron and PQQ Together?

Dose or timing may matter

The short answer

PQQ (pyrroloquinoline quinone) acts as an electron carrier and may interact with iron's redox cycling, potentially generating reactive oxygen species in the presence of excess free iron, counteracting PQQ's mitochondrial protective effects.

How to arrange timing

Separate iron and PQQ supplementation by several hours.

Reference

Reference noted for this combination: Misra HS et al. Pyrroloquinoline-quinone: a reactive oxygen species scavenger in bacteria. FEBS Lett. 2004;578(1-2):26-30

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.