Can You Take Human Milk Oligosaccharides (HMOs) and Iron Together?

May affect absorption

The short answer

Human Milk Oligosaccharides (HMOs) are soluble prebiotic fibers that may physically adsorb iron in the GI tract, reducing its bioavailability when taken simultaneously.

How to arrange timing

Separate HMO supplements and iron by at least 2 hours for optimal absorption.

Reference

Reference noted for this combination: NIH ODS; NatMed Pro Fiber Monograph; Torre M et al., Crit Rev Food Sci Nutr 1991

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.