Can You Take Guarana and Yohimbine Together?

Dose or timing may matter

The short answer

Guarana (caffeine-containing) and yohimbine both raise blood pressure through sympathomimetic mechanisms. Combined use may produce additive pressor effects.

How to arrange timing

Research suggests caution when combining stimulants that raise blood pressure. Monitor BP and heart rate.

Reference

Reference noted for this combination: Moustakas D et al. Guarana provides additional stimulation over caffeine alone. Nutrients. 2015;7(5):3684-3697

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.