Can You Take Fish Oil (Omega-3) and L-Arginine Together?

Dose or timing may matter

The short answer

Fish oil lowers blood pressure through reduced vascular resistance and anti-inflammatory effects, while L-Arginine lowers BP via nitric oxide-mediated vasodilation. The combination may produce additive hypotension.

How to arrange timing

Monitor blood pressure, especially at high supplemental doses of both.

Reference

Reference noted for this combination: Miller PE et al. Long-chain omega-3 fatty acids and blood pressure: a meta-analysis. Am J Hypertens. 2014;27(7):885-896

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.