Can You Take Enokitake Extract and Gymnema Sylvestre Together?

Dose or timing may matter

The short answer

Enokitake (Flammulina velutipes) polysaccharides have blood sugar-lowering properties. Gymnema Sylvestre reduces glucose absorption and stimulates insulin secretion. Together they may cause excessive blood sugar reduction.

How to arrange timing

Monitor blood sugar closely when combining Enokitake extract with Gymnema Sylvestre, especially if diabetic.

Reference

Reference noted for this combination: Yang W et al., International Journal of Biological Macromolecules, 2015; Baskaran K et al., J Ethnopharmacol, 1990

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.