Can You Take Digestive Enzymes and Probiotics Together?

May affect absorption

The short answer

Digestive enzymes (especially protease) may partially break down probiotic organisms if taken at the exact same time.

How to arrange timing

Take probiotics 30 minutes before meals; take digestive enzymes with meals.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.