Can You Take Citrulline and L-Arginine Together?

Use extra care with this pair

The short answer

Citrulline is converted to arginine in the body. Supplementing both may lead to excessive arginine/NO levels, potentially causing hypotension or GI distress.

How to arrange timing

Choose one or the other for NO boosting. If using both, start with lower doses.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.