Can You Take Chamomile and Melatonin Together?

Use extra care with this pair

The short answer

Chamomile's apigenin binds GABA-A receptors while melatonin promotes sleep via melatonin receptors; combined sedation may be excessive.

How to arrange timing

If combining, start with lower doses and avoid tasks requiring alertness.

Reference

Reference noted for this combination: Srivastava et al., 2010, Mol Med Report

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.