Can You Take Catalase and Quercetin Together?

Dose or timing may matter

The short answer

Catalase breaks down hydrogen peroxide, while Quercetin can generate reactive oxygen species (ROS) as part of its pro-oxidant activity at high doses. Catalase may neutralize the beneficial ROS signaling triggered by quercetin's hormetic effects.

How to arrange timing

If relying on quercetin's hormetic pro-oxidant effects, consider separating it from catalase supplementation.

Reference

Reference noted for this combination: Boots AW, et al. In vitro and ex vivo anti- and pro-oxidant activity of quercetin. Eur J Pharmacol. 2008;585(2-3):325-337.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.