Can You Take Caffeine and Magnolia Bark Together?

Dose or timing may matter

The short answer

Caffeine stimulates the CNS while magnolia bark's honokiol promotes GABAergic sedation; they may cancel each other's effects.

How to arrange timing

Separate by several hours; use caffeine in the morning, magnolia bark at night.

Reference

Reference noted for this combination: Kuribara et al., 2000, J Pharm Pharmacol

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.