Can You Take Black Cohosh and Red Yeast Rice Together?

Use extra care with this pair

The short answer

Black Cohosh and Red Yeast Rice are both independently hepatotoxic. This combination may be encountered in menopause management (Black Cohosh) combined with cholesterol management (Red Yeast Rice).

How to arrange timing

Monitor liver function if using both. Consider non-hepatotoxic alternatives for either menopause or cholesterol management.

Reference

Reference noted for this combination: Mahady GB et al., Menopause 2008; Björnsson ES, Clin Liver Dis 2017

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.