Can You Take Bile Salts and Vitamin D3 Together?

May affect absorption

The short answer

Bile salts enhance the absorption of fat-soluble vitamins including Vitamin D3. Excessive bile salt supplementation may lead to increased Vitamin D3 uptake beyond intended levels.

How to arrange timing

If taking both bile salts and Vitamin D3, monitor your Vitamin D levels as bile salts enhance its absorption. Adjust dosage if needed.

Reference

Reference noted for this combination: Dawson-Hughes B, et al. Estimates of optimal vitamin D status. Osteoporos Int. 2005;16(7):713-716.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.