Can You Take Berberine and Fish Oil (Omega-3) Together?

May affect absorption

The short answer

Berberine causes GI cramping and diarrhea, while Fish Oil can cause nausea and loose stools. Combined use may worsen digestive discomfort.

How to arrange timing

Separate by at least 2 hours.

Reference

Reference noted for this combination: Yin et al., 2012 — Berberine; Examine.com — Fish Oil

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.