Can You Take Baicalein and Iron Together?

May affect absorption

The short answer

Baicalein is a flavone with multiple hydroxyl groups that strongly chelate iron. Research shows baicalein can form stable iron complexes, reducing both baicalein bioactivity and iron absorption.

How to arrange timing

Separate Baicalein and iron supplements by at least 2 hours to preserve the bioavailability of both.

Reference

Reference noted for this combination: Perez CA, et al. Iron-binding and anti-Fenton properties of baicalein and baicalin. J Inorg Biochem. 2009;103(3):326-332.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.