Can You Take Ashwagandha and Vitamin B3 Together?

Use extra care with this pair

The short answer

Both Ashwagandha (emerging hepatotoxicity reports) and high-dose Niacin (dose-dependent hepatotoxicity) may stress the liver. Their combination, increasingly common in wellness regimens, warrants liver function awareness.

How to arrange timing

Use standard doses and monitor for signs of liver stress. If liver enzymes are already elevated, consider using one rather than both.

Reference

Reference noted for this combination: Björnsson HK et al., J Hepatol 2020; Guyton JR, Am J Cardiol 1998

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.