Can You Take Ashwagandha and Phosphatidylserine Together?

Dose or timing may matter

The short answer

Both Ashwagandha and Phosphatidylserine may reduce cortisol levels. Combined use may produce additive cortisol suppression, potentially leading to excessive cortisol reduction.

How to arrange timing

Research suggests monitoring for signs of low cortisol (fatigue, lightheadedness) when combining these supplements.

Reference

Reference noted for this combination: Journal of the International Society of Sports Nutrition, 2008; 5: 11

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.