Can You Take Apple Cider Vinegar Supplement and Berberine Together?

Dose or timing may matter

The short answer

Berberine activates AMPK while Apple Cider Vinegar improves insulin sensitivity and delays gastric emptying. Both lower postprandial blood sugar and their effects may be additive.

How to arrange timing

Monitor blood sugar when combining, particularly around meals.

Reference

Reference noted for this combination: Metabolism 2008; European Journal of Clinical Nutrition 2005

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.