Can You Take Alpha-GPC and CDP-Choline Together?

May affect absorption

The short answer

Both CDP-Choline and Alpha-GPC increase acetylcholine levels. Combining them may lead to excessive cholinergic stimulation, causing headaches or GI distress.

How to arrange timing

Use either CDP-Choline or Alpha-GPC, not both simultaneously. If combining, reduce doses of each.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.