Does Spicy foods Affect Digestive Enzymes?

May affect absorption or how you feel

The short answer

Capsaicin increases gastric acid secretion, which may denature acid-sensitive digestive enzymes before they reach the small intestine.

How to arrange timing

Take digestive enzymes at least 1 hour apart from spicy meals, or use enteric-coated formulas.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.