Does Spicy foods Affect Deglycyrrhizinated Licorice?

Amount or timing may matter

The short answer

DGL works by enhancing the gastric mucus barrier. Capsaicin irritates and thins this same barrier, counteracting DGL's protective mechanism.

How to arrange timing

Take DGL at least 2 hours apart from spicy meals.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.