Does Soy foods Affect DIM?

Amount or timing may matter

The short answer

DIM promotes estrogen metabolism toward less potent forms, but soy isoflavones add exogenous estrogenic activity, potentially opposing DIM's balancing effect.

How to arrange timing

Moderate soy intake when using DIM for estrogen metabolism support.

Reference

Reference noted for this food and supplement combination: Examine.com; Thomson et al., Nutr Rev 2016

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.