Does Caffeine Affect Vitamin B2?

May affect absorption or how you feel

The short answer

Caffeine increases urinary excretion of riboflavin (B2) through its diuretic mechanism.

How to arrange timing

Take riboflavin at least 1 hour apart from coffee.

Reference

Reference noted for this food and supplement combination: NIH ODS 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.