Does Caffeine Affect California Poppy?

Amount or timing may matter

The short answer

California poppy has sedative and anxiolytic effects via GABA receptor modulation. Caffeine directly opposes these calming effects.

How to arrange timing

Avoid caffeine at least 6 hours before taking California poppy for sleep or anxiety.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.