Does Alcohol Affect Vitamin C?

Amount or timing may matter

The short answer

Alcohol depletes vitamin C stores and increases oxidative stress, reducing the effectiveness of vitamin C supplementation.

How to arrange timing

Take vitamin C at least 4 hours apart from alcohol consumption.

Reference

Reference noted for this food and supplement combination: NIH ODS 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.