Does Alcohol Affect GABA?

Use extra care with this combination

The short answer

Alcohol enhances GABA receptor activity. Supplemental GABA with alcohol may cause excessive CNS depression, drowsiness, and impaired motor function.

How to arrange timing

Do not take GABA supplements within 6 hours of alcohol consumption.

Reference

Reference noted for this food and supplement combination: Examine.com 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.