Can You Take Sulforaphane and Vitamin K1 Together?

Dose or timing may matter

The short answer

Sulforaphane induces Phase II detoxification enzymes (including those in the liver) that may increase the metabolism and clearance of vitamin K1, potentially reducing its anticoagulant-balancing effects.

How to arrange timing

If on vitamin K therapy (e.g., for anticoagulant management), monitor INR when adding sulforaphane supplements.

Reference

Reference noted for this combination: Fahey JW et al. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori. Proc Natl Acad Sci USA. 2002;99(11):7610-7615

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.