Can You Take Skullcap and Valerian Root Together?

Use extra care with this pair

The short answer

Both skullcap and valerian act on GABA receptors; combining may lead to excessive sedation.

How to arrange timing

Use one at a time or reduce doses if combining.

Reference

Reference noted for this combination: Awad et al., 2003, Phytomedicine

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.