Can You Take Shiitake Extract and Turmeric / Curcumin Together?

May affect absorption

The short answer

Shiitake contains eritadenine with mild antiplatelet activity. Turmeric (curcumin) also inhibits platelet aggregation. Combined use may slightly increase bleeding tendency through additive mechanisms.

How to arrange timing

Generally safe, but watch for easy bruising when combining Shiitake extract with Turmeric at high doses.

Reference

Reference noted for this combination: Enman J et al., Journal of the Science of Food and Agriculture, 2007; Lestari ML, Indrayanto G. Profiles Drug Subst Excip Relat Methodol. 2014

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.