Can You Take Mucuna Pruriens and St. John's Wort Together?

Use extra care with this pair

The short answer

St. John's Wort affects serotonin and dopamine. Combining with Mucuna (L-DOPA) risks serotonin syndrome or dopaminergic excess.

How to arrange timing

Avoid this combination.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.