Can You Take Lumbrokinase and Nattokinase Together?

Use extra care with this pair

The short answer

Both Lumbrokinase and Nattokinase are fibrinolytic enzymes that break down fibrin. Combined use may excessively enhance clot dissolution and increase bleeding risk.

How to arrange timing

Consider using only one fibrinolytic enzyme supplement at a time. If combining Lumbrokinase with Nattokinase, start with lower doses and monitor for signs of easy bruising or prolonged bleeding.

Reference

Reference noted for this combination: Pais-Morales J et al., Journal of Thrombosis and Haemostasis, 2020; Natural Medicines Comprehensive Database

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.