Can You Take L-Arginine and Nattokinase Together?

Dose or timing may matter

The short answer

L-Arginine lowers blood pressure via nitric oxide while nattokinase has fibrinolytic and mild hypotensive effects. The combination may produce additive blood pressure reduction.

How to arrange timing

Monitor blood pressure when using both supplements, especially at higher doses.

Reference

Reference noted for this combination: Kim JY et al. Effects of nattokinase on blood pressure. Hypertens Res. 2008;31(8):1583-1588

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.