Can You Take Kava and Phenibut Together?

Use extra care with this pair

The short answer

Both kava and phenibut are potent GABAergic agents; combined use may cause pronounced CNS depression.

How to arrange timing

Avoid combining these two potent sedatives.

Reference

Reference noted for this combination: Sarris et al., 2013, J Clin Psychopharmacol

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.