Can You Take GABA and Skullcap Together?

Use extra care with this pair

The short answer

GABA supplementation combined with skullcap's baicalin (a GABA-A modulator) may cause excessive sedation.

How to arrange timing

Use one at a time if alertness is needed.

Reference

Reference noted for this combination: Awad et al., 2003, Phytomedicine

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.