← Back to all supplement pairs
Can You Take Folate and Vitamin B12 Together?
Dose or timing may matter
The short answer
High-dose folic acid supplementation can mask the symptoms of vitamin B12 deficiency (megaloblastic anemia), potentially delaying diagnosis of B12 deficiency.
How to arrange timing
If supplementing folate, ensure adequate B12 intake (or test B12 levels periodically).
Reference
Reference noted for this combination: NIH ODS 2024
Important context
Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.