Can You Take Doxycycline (Low Dose) and Iron Together?

Use extra care with this pair

The short answer

Iron forms insoluble chelates with doxycycline, reducing absorption of both. This is a well-established drug-mineral interaction.

How to arrange timing

Separate low-dose doxycycline from iron supplements by at least 3 hours.

Reference

Reference noted for this combination: Product labeling; Neuvonen PJ. Drug Metab Rev. 1976

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.