Can You Take DMHA and Hordenine Together?

Use extra care with this pair

The short answer

Both DMHA and hordenine are sympathomimetic compounds. Hordenine inhibits norepinephrine reuptake while DMHA stimulates its release. The combination amplifies adrenergic tone and may cause cardiovascular overstimulation.

How to arrange timing

Avoid stacking these stimulants. The combined effect on norepinephrine signaling increases cardiovascular risk significantly.

Reference

Reference noted for this combination: Barwell CJ et al. Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. J Pharm Pharmacol. 1989;41(6):421-423

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.