Can You Take St. John's Wort and CoQ10 Together?

Dose or timing may matter

The short answer

St. John's Wort may reduce CoQ10 levels by inducing its metabolism via CYP enzymes.

How to arrange timing

Avoid combining or monitor CoQ10 levels.

Reference

Reference noted for this combination: Examine.com 2024

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.