Can You Take Copper and Mangiferin Together?

May affect absorption

The short answer

Mangiferin chelates divalent metal ions including copper through its catechol and carbonyl groups, potentially reducing copper bioavailability.

How to arrange timing

Separate Mangiferin and copper supplements by at least 2 hours.

Reference

Reference noted for this combination: Pardo-Andreu GL, et al. Mangifera indica L. (Vimang) protection against serum oxidative stress in elderly humans. Arch Med Res. 2006;37(1):158-164.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.