Can You Take CBD (Cannabidiol) and L-Arginine Together?

Dose or timing may matter

The short answer

CBD has vasodilatory properties and can lower blood pressure, while L-Arginine produces nitric oxide for vasodilation. Combined use may cause additive hypotensive effects.

How to arrange timing

Monitor blood pressure when combining, especially at higher doses of each.

Reference

Reference noted for this combination: Jadoon KA et al. A single dose of cannabidiol reduces blood pressure. JCI Insight. 2017;2(12):e93760

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.