Can You Take Calcium and Uva Ursi Together?

Dose or timing may matter

The short answer

Uva ursi's active compound (arbutin/hydroquinone) is renally processed, and its diuretic effect alters calcium excretion dynamics. Calcium supplementation may increase renal calcium load while uva ursi increases urine flow.

How to arrange timing

Avoid long-term concurrent use. If combining short-term, monitor hydration and urinary calcium levels.

Reference

Reference noted for this combination: Schindler G et al. J Clin Pharmacol. 2002;42(8):920-927; Curhan GC et al. N Engl J Med. 1993;328(12):833-838

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.