Can You Take Caffeine and Phenylpiracetam Together?

Dose or timing may matter

The short answer

Phenylpiracetam has psychostimulant properties and increases physical stamina, while caffeine is a CNS stimulant. Combining them may cause overstimulation, anxiety, elevated heart rate, and difficulty sleeping.

How to arrange timing

Reduce caffeine intake when using Phenylpiracetam. Start with a lower dose of both and avoid combining in the afternoon or evening.

Reference

Reference noted for this combination: Zvejniece L, et al. Investigation into stereoselective pharmacological activity of phenotropil. Basic Clin Pharmacol Toxicol. 2011;109(5):407-412.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.