Can You Take Caffeine and Passionflower Together?

Dose or timing may matter

The short answer

Caffeine may counteract passionflower's GABAergic calming effects, reducing the effectiveness of both.

How to arrange timing

Separate intake by at least 3-4 hours.

Reference

Reference noted for this combination: Ngan & Conduit, 2011, Phytother Res

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.