Can You Take Caffeine and Kratom Together?

Dose or timing may matter

The short answer

Caffeine may counteract the sedative effects of kratom's opioid-active alkaloids at higher doses, while at lower kratom doses both are stimulatory.

How to arrange timing

Be aware of unpredictable interactions depending on kratom dosage.

Reference

Reference noted for this combination: Swogger et al., 2015, J Psychoactive Drugs

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.