Can You Take Bromelain and Nattokinase (Enteric-Coated) Together?

Use extra care with this pair

The short answer

Both Bromelain and Nattokinase (Enteric-Coated) are fibrinolytic enzymes that break down fibrin. Combined use may excessively enhance clot dissolution and increase bleeding risk.

How to arrange timing

Consider using only one fibrinolytic enzyme supplement at a time. If combining Bromelain with Nattokinase (Enteric-Coated), start with lower doses and monitor for signs of easy bruising or prolonged bleeding.

Reference

Reference noted for this combination: Pais-Morales J et al., Journal of Thrombosis and Haemostasis, 2020; Natural Medicines Comprehensive Database

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.