Can You Take Berberine and White Willow Bark Together?

May affect absorption

The short answer

Berberine causes GI cramping and diarrhea. White Willow Bark contains salicin which can irritate the stomach lining. Combined use may significantly increase GI distress.

How to arrange timing

Separate by at least 2 hours. Take White Willow Bark with food.

Reference

Reference noted for this combination: Examine.com — Berberine; Vlachojannis et al., 2009 — Willow bark GI effects

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.