Can You Take Berberine and Oregon Grape Together?

Dose or timing may matter

The short answer

Oregon Grape root contains berberine. Combining with berberine supplements may lead to excessive intake, potentially causing gastrointestinal issues and hypoglycemia.

How to arrange timing

Avoid combining Oregon Grape with berberine supplements. Choose one source of berberine.

Reference

Reference noted for this combination: Examine.com; Natural Medicines Comprehensive Database

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.