Can You Take Berberine and Mulberry Leaf Extract Together?

Dose or timing may matter

The short answer

Berberine activates AMPK while Mulberry Leaf Extract contains DNJ (1-deoxynojirimycin) which inhibits alpha-glucosidase. Both significantly lower postprandial blood sugar.

How to arrange timing

Monitor blood sugar when combining these potent glucose-lowering supplements.

Reference

Reference noted for this combination: Metabolism 2008; Diabetes Care 2007

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.