Can You Take Berberine and Coptis Rhizome Together?

Dose or timing may matter

The short answer

Coptis Rhizome (Huang Lian) is one of the richest natural sources of berberine. Combining with berberine supplements results in redundant dosing.

How to arrange timing

Do not combine Coptis Rhizome with berberine supplements. Use one or the other.

Reference

Reference noted for this combination: Chinese Pharmacopoeia; Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.