Can You Take Berberine and Cryptolepis Together?

Dose or timing may matter

The short answer

Cryptolepis has potent hypoglycemic activity. Combining with berberine (which also lowers blood sugar) may cause additive hypoglycemic effects.

How to arrange timing

Monitor blood sugar closely when combining Cryptolepis with berberine. Reduce doses if needed.

Reference

Reference noted for this combination: Luo J, et al. Phytother Res. 1998;12:S28-S30

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.