Can You Take Adrafinil and Green Tea Extract (EGCG) Together?

Use extra care with this pair

The short answer

Adrafinil is metabolized in the liver and may elevate liver enzymes with chronic use. High-dose EGCG is a documented hepatotoxin. Combined use may increase liver metabolic stress.

How to arrange timing

Monitor liver function if combining. Consider cycling adrafinil use and keeping EGCG at standard doses.

Reference

Reference noted for this combination: LiverTox (NIH/NLM); Navarro VJ et al., Hepatology 2017

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.